Human leukocyte antigen class I alleles and cervical neoplasia: no heterozygote advantage.
نویسندگان
چکیده
Interdisciplinary Studies Section, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 [S. S. W., A. H., M. S., M. E. S.]; Laboratory of Genetic Diversity, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21701-1201 [X. G., P. K., M. C.]; Proyecto Epidemiologico Guanacaste, Guanacaste, Costa Rica [R. H., M. C. B.]; Lombardi Cancer Center, Georgetown University, Washington, DC 20007 [W. A. B.]; Graduate Hospital, Philadelphia, Pennsylvania 19146 [M. D. G.]; Division of Gynecologic Oncology, George Washington University, Washington, DC 20052 [L. M.]; Milton S. Hershey Medical Center, Hershey, Pennsylvania 17033 [R. M.]; Yale University School of Medicine, New Haven, Connecticut 06510 [P. E. S.]; Kaiser Foundation Research Institute, Oakland, California 94612 [A. G. G.]; and Albert Einstein College of Medicine, Bronx, New York 10461 [R. D. B.]
منابع مشابه
Human Leukocyte Antigen Class I and II Variants in Yemeni Patients with Chronic Renal Failure
Background: Human leukocyte antigens (HLAs) are found to be significant genetic factors concerning the susceptibility of an individual to certain diseases. Objective: To determine the association between variants of class I (A and B) and class II (DRB1) HLA alleles and chronic renal failure (CRF), compared with healthy controls, in Yemen. Methods: A case-control study in the Urology and Nephrol...
متن کاملThe Frequency of Human Leukocyte Antigen Class I and II Alleles and the Relationship Between Haplotypes in Gilaks Population of Iran
Background: The Human Leukocyte Antigen (HLA) is the most polymorphic region in human genome. Moreover, HLA haplotype frequencies are largely used in transplantation, the treatment of autoimmune diseases, and population-based studies. The present study aimed to determine HLA-A, -B, -DR alleles and haplotype frequencies in 88 unrelated donors of Iranian Gilak ethnic group, by Polymerase Chain Re...
متن کاملInvestigation of Human Leukocyte Antigen (HLA) Class I and II Alleles and Hepatitis C Virus (HCV) Genotypes in Patients Infected with HCV
Hepatitis C virus (HCV) is a major public health problem with more than 130-180 million people infected worldwide. Several studies in different populations have reported the association of human leukocyte antigen (HLA) genotypes, and HCV viral load, and genotypes. The aim of this study was to investigate a possible association between HLA class I and II alleles in HCV-infected patients and heal...
متن کاملAnalysis of Human Leukocyte Antigen class II Gene Polymorphism in Iranian Patients with Papillon-Lefevre Syndrome: a Family Study
Background: Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and early development of aggressive pe-riodontitis. Although cathepsin C (CTSC) gene mutations have been established in about 70-80% of PLS patients, it is assumed that the patients may have dysfunctioning of immune defense mechanisms. Objective: To assess the associat...
متن کاملAssociation between HLA-Class I and HLA-Class II Alleles and Mycobacterium Tuberculosis Infection in Iraqi Patients from Baghdad City
Background: Pulmonary tuberculosis (PT) is one of the endemic diseases in Iraq, and among the suggested predisposing factors are alleles of the human leukocyte antigen (HLA) system. We sought to investigate the association between HLA-class I (A and B) and -class II (DR and DQ) alleles in a sample of PT Iraqi patients.Methods: lymphocytes of 105 PT patients and 40 controls were phenotyped for H...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
دوره 11 4 شماره
صفحات -
تاریخ انتشار 2002